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INRA
24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal

Plantes et Système de cultures Horticoles

Zone de texte éditable et éditée et rééditée

Valentina Baldazzi

Researcher

Valentina BALDAZZI

Chargé de Recherche

Lab. Plantes et Systèmes de culture Horticoles

Equipe : Ecophysiologie des Plantes Horticoles

CONTACTS

INRA

UR1115 Plantes et Systèmes de culture Horticoles

Domaine Saint Paul, Site Agroparc

CS 40509

84914 Avignon Cedex 9

Tel : +33 (0)4 32 72 24 47

Email : valentina.baldazzi@avignon.inra.fr

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  • POSITIONS AND EDUCATION

Physicist by formation, I have always been attracted by biological systems and interdisciplinary research. In particular, theoretical approaches and mathematical modeling offer a useful tool to investigate the charming complexity of this kind of systems, looking for some fundamental principles or simply testing our capacity to describe their behavior.

During my thesis and post-doctoral activities, I had the opportunity to familiarize with several biological systems, from the molecular to the cellular level, using different approaches and mathematical formalisms (quantitative and qualitative approaches, discrete and continuous models, stochastic and deterministic descriptions).

I'm currently interested in plant biology and ecophysiology, trying to understand the links between ecological factors (i.e environmental conditions, cultural practices etc) and the underlying molecular mechanisms that determine fruit quality and composition. The different scales involved and the lack of detailed knowledge can make the system difficult to be dealt with classical ODE methods. Several strategies will be explored, including reduction methods, based on ANN, statistical analysis or time-scale approximations, qualitative and hybrid approaches.

A sketch of my CV and main research experiences is reported in the following.

  • EDUCATION AND RESEARCH EXPERIENCES

Since 2010 Researcher, Unité PSH, INRA, Avignon, France

Modeling fruit quality and composition in relation to genetic, plant and environmental factors.

2007-2009 Post-doc student, IBIS, INRIA Rhône-Alpes, Montbonnot, France.

Mathematical modeling of biochemical networks; integration of genetic-metabolic levels of regulation. Nutritional stress response in E. coli.Qualitative approaches (piecewise-linear equations) and reduction methods, based on quasi-steady-state approximation and metabolic control analysis.

2006-2007 Post-doc student, IAC, National Research Council (CNR), Rome.

Development of an immune system simulator based on stochastic cellular automata. Hybrid model (partial differential equations + automata) for the description of lymphocytes traffic and encounters inside lymph nodes.

2002-2006 PhD in Physics, University of Rome Tor Vergata and University of Strasbourg Louis Pasteur

Modeling biophysical experiments through statistical physics and computer (Monte Carlo)simulation. Bayesian inference of DNA sequence from unzipping experiments.

  • SELECTED PUBLICATIONS

International journals

V. Baldazzi, S. Cocco, E. Marinari, R. Monasson

'Inference of DNA sequences from mechanical unzipping : an ideal-case study' , Physical Review Letter, 96, 128102 (2006)

V. Baldazzi, S. Bradde, S. Cocco, E. Marinari, R. Monasson 'Inferring DNA sequences from unzipping experiments : the large-bandwidth case',

Physical Review E, 75, 011904 (2007)

V. Baldazzi, F. Castiglione, M. Bernaschi

'An enhanced agent based model of the immune system response',

Cellular Immunology, 244, 77-79 (2006)

D. Ropers, V. Baldazzi, H. De Jong

'Model Reduction Using Piecewise-Linear Approximations Preserves Dynamic Properties of the Carbon Starvation Response in Escherichia coli'

IEEE/ACM Transactions on Computational Biology and Bioinformatics (2009), IEEE computer Society Digital Library, http://doi.ieeecomputersociety.org/10.1109/TCBB.2009.49

V. Baldazzi, P. Paci, M. Bernaschi, F. Castiglione

'Modeling lymphocyte homing and encounters in lymph nodes'

BMC Bioinformatics, 10, 387 (2009)

V.Baldazzi, D.Ropers, Y. Markowicz, D. Kahn, J. Geiselmann, H. De Jong

'The carbon assimilation network in Escherichia coli is densely connected and largely sign-determined by directions of metabolic fluxes'

PloS Computational Biology, 6, e1000812 (2010)

Book chapters

V.Baldazzi et al., in W. Dubitzky, J. Southgate and H. Fuss (editors), 'Understanding the Dynamics of Biological Systems : Lessons Learned from Integrative Systems Biology', Springer (to appear).