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24, chemin de Borde Rouge -Auzeville - CS52627 31326 Castanet Tolosan cedex - France

Last update: May 2021

Menu Institut Sophia Agrobiotech Logo Marque Etat - République Française Logo_INRAE_noir Logo Université Côte d'Azur CNRS

Institut Sophia Agrobiotech

Institut Sophia Agrobiotech

UMR INRA - Univ. Nice Sophia Antipolis - Cnrs


Publications :


  • Amezian D, Mehlhorn S, Vacher-Chicane C, Nauen R, Le Goff G. Spodoptera frugiperda Sf9 cells as a model system to investigate the role of detoxification gene expression in response to xenobiotics. Curr Res Insect Sci. 2022 Apr 18;2:100037. doi: 10.1016/j.cris.2022.100037.  
  • Arraes FBM, Vasquez DDN, Tahir M, Pinheiro DH, Faheem M, Freitas-Alves NS, Moreira-Pinto CE, Moreira VJV, Paes-de-Melo B, Lisei-de-Sa ME, Morgante CV, Mota APZ, Lourenço-Tessutti IT, Togawa RC, Grynberg P, Fragoso RR, de Almeida-Engler J, Larsen MR, Grossi-de-Sa MF. Integrated Omic Approaches Reveal Molecular Mechanisms of Tolerance during Soybean and Meloidogyne incognita Interactions. Plants (Basel). 2022 Oct 17;11(20):2744. doi: 10.3390/plants11202744. PMID: 36297768; PMCID: PMC9612212.
  • Basso MF, Lourenço-Tessutti IT, Moreira-Pinto CE, Mendes RAG, Paes-de-Melo B, das Neves MR, Macedo AF, Figueiredo V, Grandis A, Macedo LLP, Arraes FBM, do Carmo Costa MM, Togawa RC, Enrich-Prast A, Marcelino-Guimaraes FC, Gomes ACMM, Silva MCM, Floh EIS, Buckeridge MS, de Almeida Engler J, Grossi-d-Sa MF. Overexpression of a soybean Globin (GmGlb1-1) gene reduces plant susceptibility to Meloidogyne incognita. Planta. 2022 Sep 16;256(4):83. doi: 10.1007/s00425-022-03992-2. PMID: 36112244.
  • Eskelin K., Mirka L., Coustau C., Imani J., Kogel K-K., Poranen M. 2022. Analysis and purification of ssRNA and dsRNA molecules using asymetrical flow field-flow fractionation. Journal of Chromatography A 1683 463552
  • Fragoso RR, Arraes FBM, Lourenço-Tessutti IT, Miranda VJ, Basso MF, Ferreira AVJ, Viana AAB, Lins CBJ, Lins PC, Moura SM, Batista JAN, Silva MCM, Engler G, Morgante CV, Lisei-de-Sa ME, Vasques RM, de Almeida-Engler J, Grossi-de-Sa MF. Functional characterization of the pUceS8.3 promoter and its potential use for ectopic gene overexpression. Planta. 2022 Sep 6;256(4):69. doi: 10.1007/s00425-022-03980-6. PMID: 36066773
  • Moreira VJV, Lourenço-Tessutti IT, Basso MF, Lisei-de-Sa ME, Morgante CV, Paes-de-Melo B, Arraes FBM, Martins-de-Sa D, Silva MCM, de Almeida Engler J, Grossi-de-Sa MF. Minc03328 effector gene downregulation severely affects Meloidogyne incognita parasitism in transgenic Arabidopsis thaliana.   Planta. 2022, 255(2):44. doi: 10.1007/s00425-022-03823-4.
  • Roumani M, LeBot J, Boisbrun M, Magot F, Péré A, Robin C, Hilliou F, Larbat R. Transcriptomics and Metabolomics Analyses Reveal High Induction of the Phenolamide Pathway in Tomato Plants Attacked by the Leafminer Tuta absoluta.  Metabolites 2022, 12
  • Yainna S, Tay W T, Durand K, Fiteni E, Hilliou F, Legeai F, Clamens A-L,Gimenez S,Asokan R, Kalleshwaraswamy C M, Deshmukh S S, Meagher R L, Blanco C A, Silvie P, Brévault T, Dassou A, Kergoat G J, Walsh T, Gordon K, Nègre N, d’Alençon E, Nam K. The evolutionary process of invasion in the fall armyworm (Spodoptera frugiperda), Scientific Reports 12, 21063, 2022​


  • Gruner K., Leissing F. Sinitski D., Thieron A., Axstmann C., Baumgarten K., Reinstädler A., Winkler P., Altmann M., Fatley A., Jaouannet M., Zienkiewicz K., Feussner I., Keller H., Coustau C., Falter-Braun P., Feederle R., Bernhagen J., Panstruga R. 2021. Chemokine-like MDL proteins modulate flowering time and innate immunity in plants. Journal of Biological Chemistry 296 100611. 
  • Favery B., Coustau C. 2021. Réponse des plantes aux attaques d’insectes et de nématodes. In : L’immunité des plantes (Lannou C, Roby D., Ravigné V., Hannachi M., Moury B., coord), Editions Quae, Versailles, pp 77-86.
  • Amezian D, Nauen R, Le Goff G. Comparative analysis of the detoxification gene inventory of four major Spodoptera pest species in response to xenobiotics. Insect Biochem Mol Biol. 2021 Aug 29;138:103646. doi: 10.1016/j.ibmb.2021.103646.
  • Le Goff G, Nauen R. Recent Advances in the Understanding of Molecular Mechanisms of Resistance in Noctuid Pests. Insects. 2021 July ; 12(8). doi : 10.3390/insects12080674
  • Chertemps T, Le Goff G, Maïbèche M, Hilliou F. Detoxification gene families in Phylloxera: Endogenous functions and roles in response to the environment. Comp Biochem Physiol Part D Genomics Proteomics. 2021 Jun 25;40:100867. doi: 10.1016/j.cbd.2021.100867.
  • Hilliou F, Chertemps T, Maïbèche M, Le Goff G. Resistance in the Genus Spodoptera: Key Insect Detoxification Genes. Insects. 2021 Jun 11;12(6):544. doi: 10.3390/insects12060544.
  • Amezian D, Nauen R, Le Goff G. Transcriptional regulation of xenobiotic detoxification genes in insects - An overview. Pestic Biochem Physiol. 2021 May;174:104822. doi: 10.1016/j.pestbp.2021.104822.
  • Gauthier J, Boulain H, van Vugt JJFA, Baudry L, Persyn E, Aury JM, Noel B, Bretaudeau A, Legeai F, Warris S, Chebbi MA, Dubreuil G, Duvic B, Kremer N, Gayral P, Musset K, Josse T, Bigot D, Bressac C, Moreau S, Periquet G, Harry M, Montagné N, Boulogne I, Sabeti-Azad M, Maïbèche M, Chertemps T, Hilliou F, Siaussat D, Amselem J, Luyten I, Capdevielle-Dulac C, Labadie K, Merlin BL, Barbe V, de Boer JG, Marbouty M, Cônsoli FL, Dupas S, Hua-Van A, Le Goff G, Bézier A, Jacquin-Joly E, Whitfield JB, Vet LEM, Smid HM, Kaiser L, Koszul R, Huguet E, Herniou EA, Drezen JM. Chromosomal scale assembly of parasitic wasp genome reveals symbiotic virus colonization. Commun Biol. 2021 Jan 22;4(1):104. doi: 10.1038/s42003-020-01623-8.
  • R4P network. Monitoring systems for resistance to plant protection products across the world: Between redundancy and complementarity. Pest Manag Sci. 2021 Jun;77(6):2697-2709. doi: 10.1002/ps.6275.


  • Gimenez S, Abdelgaffar H, Le Goff G, Hilliou F, Blanco CA, Hänniger S, Bretaudeau A, Legeai F, Nègre N, Jurat-Fuentes JL, d'Alençon E, Nam K. Adaptation by copy number variation increases insecticide resistance in the fall armyworm. Communications Biology 2020 Nov 12;3(1):664. doi: 10.1038/s42003-020-01382-6. PMID: 33184418
  • Jaouannet M, Pavaux AS, Pagnotta S, Pierre O, Michelet C, Marro S, Keller H, Lemée R, Coustau C. (2020). Atypical membrane-anchored cytokine MIF in a marine dinoflagellate. Microorganisms, 8, 1263, doi:10.3390/microorganisms8091263
  • Liu S., Jaouannet M., Dempsey DA, JImani J., Coustau C, Kogel KH. (2020). RNA-based technologies for insect control in plant production. Biotechnology Advances, 39, 107463,
  • Rispe C, Legeai F, Nabity PD, Fernández R, Arora AK, Baa-Puyoulet P, Banfill CR, Bao L, Barberà M, Bouallègue M, Bretaudeau A, Brisson JA, Calevro F, Capy P, Catrice O, Chertemps T, Couture C, Delière L, Douglas AE, Dufault-Thompson K, Escuer P, Feng H, Forneck A, Gabaldón T, Guigó R, Hilliou F, Hinojosa-Alvarez S, Hsiao YM, Hudaverdian S, Jacquin-Joly E, James EB, Johnston S, Joubard B, Le Goff G, Le Trionnaire G, Librado P, Liu S, Lombaert E, Lu HL, Maïbèche M, Makni M, Marcet-Houben M, Martínez-Torres D, Meslin C, Montagné N, Moran NA, Papura D, Parisot N, Rahbé Y, Lopes MR, Ripoll-Cladellas A, Robin S, Roques C, Roux P, Rozas J, Sánchez-Gracia A, Sánchez-Herrero JF, Santesmasses D, Scatoni I, Serre RF, Tang M, Tian W, Umina PA, van Munster M, Vincent-Monégat C, Wemmer J, Wilson ACC, Zhang Y, Zhao C, Zhao J, Zhao S, Zhou X, Delmotte F, Tagu D (2020). The genome sequence of the grape phylloxera provides insights into the evolution, adaptation, and invasion routes of an iconic pest. BMC Biology, 18(1):90. doi: 10.1186/s12915-020-00820-5.PMID: 32698880
  • Ruttanaphan T, de Sousa G, Pengsook A, Pluempanupat W, Huditz HI, Bullangpoti V, Le Goff G (2020). A Novel Insecticidal Molecule Extracted from Alpinia galanga with Potential to Control the Pest Insect Spodoptera frugiperda. Insects, 11(10):686. doi: 10.3390/insects11100686. PMID: 33050622
  • Tetreau G, Dhinaut J, Galinier R, Audant-Lacour P, Voisin SN, Arafah K, Chogne M, Hilliou F, Bordes A, Sabarly C, Chan P, Walet-Balieu ML, Vaudry D, Duval D, Bulet P, Coustau C, Moret Y, Gourbal B (2020). Deciphering the molecular mechanisms of mother-to-egg immune protection in the mealworm beetle Tenebrio molitor. PLOS Pathogens, 16 (10). Doi :10.1371/journal.ppat.1008935.


  • Castella, C., Pauron, D., Hilliou, F., Trang, V. T., Zucchini-Pascal, N., Gallet, A. and Barbero, P. (2019). "Transcriptomic analysis of Spodoptera frugiperda Sf9 cells resistant to Bacillus thuringiensis Cry1Ca toxin reveals that extracellular Ca(2+), Mg(2+) and production of cAMP are involved in toxicity." Biology Open 8(4). pii: bio.037085. doi: 10.1242/bio.037085. PMC6503997
  • Michelet C, Danchin E, Jaouannet M, Bernhagen J, Panstruga R, Kogel KH, Keller H and Coustau C. (2019). Cross-kingdom analysis of diversity, evolutionary history, and site selection within the eukaryotic Macrophage Migration Inhibitory Factor superfamily. Genes, 10, 740; doi:10.3390/genes10100740.
  • Ramirez-Prado JS, Latrasse D, Rodriguez-Granados NY, Huang Y, Manza-Mianza D, Brik-Chaouche R, Jaouannet M, Citerne S, Bendahmane A, Hirt H, Raynaud C, Benhamed M. (2019). The Polycomb protein LHP1 regulates Arabidopsis thaliana stress responses through the repression of the MYC2-dependent branch of immunity. Plant Journal 100(6):1118-1131. doi: 10.1111/tpj.14502.
  • Ruttanaphan T, Pluempanupat W, Aungsirisawat C, Boonyarit P, Le Goff G, Bullangpoti V. J. (2019). Effect of Plant Essential Oils and Their Major Constituents on Cypermethrin Tolerance Associated Detoxification Enzyme Activities in Spodoptera litura (Lepidoptera: Noctuidae). Journal of Economic Entomology. 112(5):2167-2176. doi: 10.1093/jee/toz126. PMID: 31139824


  • Beaulieu, R., Grand, E., Stasik, I., Attoumbré, J., Chesnais, Q., Gobert, V., Ameline, A., Giordanengo, P., and Kovensky, J. (2018). Synthesis and Insecticidal Activities of Novel Solanidine Derivatives. Pest Management Science 0. DOI: 10.1002/ps.5180


  • Adema, C.M., Hillier, L.W., Jones, C.S., Loker, E.S., Knight, M., Minx, P., Oliveira, G., Raghavan, N., Shedlock, A., Amaral, L.R. do, et al. (2017). Whole genome analysis of a schistosomiasis-transmitting freshwater snail. Nature Communications 8, ncomms15451. DOI: 10.1038/ncomms15451
  • Cheng, T., Wu, J., Wu, Y., Chilukuri, R.V., Huang, L., Yamamoto, K., Feng, L., Li, W., Chen, Z., Guo, H., et al. (2017). Genomic adaptation to polyphagy and insecticides in a major East Asian noctuid pest. Nature Ecology & Evolution 1, 1747. DOI: 10.1038/s41559-017-0314-4
  • Gentekaki, E., Curtis, B.A., Stairs, C.W., Klimeš, V., Eliáš, M., Salas-Leiva, D.E., Herman, E.K., Eme, L., Arias, M.C., Henrissat, B., et al. (2017). Extreme genome diversity in the hyper-prevalent parasitic eukaryote Blastocystis. PLOS Biology 15, e2003769. DOI: 10.1371/journal.pbio.2003769
  • Gouin, A., Bretaudeau, A., Nam, K., Gimenez, S., Aury, J.-M., Duvic, B., Hilliou, F., Durand, N., Montagné, N., Darboux, I., et al. (2017). Two genomes of highly polyphagous lepidopteran pests ( Spodoptera frugiperda , Noctuidae) with different host-plant ranges. Scientific Reports 7, 11816. DOI: 10.1038/s41598-017-10461-4


  • Baron, O.L., Deleury, E., Reichhart, J.-M., and Coustau, C. (2015). The LBP/BPI multigenic family in invertebrates: Evolutionary history and evidences of specialization in mollusks. Developmental and Comparative Immunology, 57: 20-30
  • Coustau, C., Kurtz, J., and Moret, Y. (2016). A Novel Mechanism of Immune Memory Unveiled at the Invertebrate–Parasite Interface. Trends in Parasitology. DOI: 10.1016/
  • Kanost,M.R., Arrese, E.L., Cao, X., et al. (2016). Multifaceted biological insights from a draft genome sequence of the tobacco hornworm moth, Manduca sexta. Insect Biochemistry and Molecular Biology, 76: 118-147
  • Le Goff, G., Hilliou, F. (2016). Resistance evolution in Drosophila: the case of CYP6G1. Pest Management Science, DOI: 10.1002/ps.4470
  • Verheggen F., Verhaeghe A., Giordanengo, P., Tassus X., Escobar-Gutierrez A. (2016) Walnut husk fly, Rhagoletis completa (Cresson) invades Europe: Invasion potential and prevention strategies. Applied Entomology and Zoology, DOI 10.1007/s13355-016-0459-7


  • Coelho, A., Fraichard, S., Le Goff, G., Faure, P., Artur, Y., Ferveur, J.-F., and Heydel, J.-M. (2015). Cytochrome P450-Dependent Metabolism of Caffeine in Drosophila melanogaster. PLoS ONE 10, e0117328. DOI: 10.1371/journal.pone.0117328
  • Coustau, C., Gourbal, B., Duval, D., Yoshino, T.P., Adema, C.M., and Mitta, G. Advances in gastropod immunity from the study of the interaction between the snail Biomphalaria glabrata and its parasites: A review of research progress over the last decade. Fish & Shellfish Immunology. DOI: 10.1016/j.fsi.2015.01.036
  • Feyereisen, R., Dermauw, W., and Van Leeuwen, T. (2015). Genotype to phenotype, the molecular and physiological dimensions of resistance in arthropods. Pesticide Biochemistry and Physiology. DOI: 10.1016/j.pestbp.2015.01.004
  • Mondédji, A.D., Nyamador, W.S., Amévoin, K., Ketoh, G.K., Giordanengo P. and Glitho I.A. (2015). Treatment and post-treatment effects of neem leaves extracts on Plutella xylostella (Lepidoptera: Plutellidae). African Journal of Agricultural Research 2015, 10(6): 472-476
  • Naessens, E., Dubreuil, G., Giordanengo, P., Baron, O.L., Minet-Kebdani, N., Keller, H., and Coustau, C. (2015) A Secreted MIF Cytokine Enables Aphid Feeding and Represses Plant Immune Responses. Current Biology. Published Online: June 25, 2015. DOI: 10.1016/j.cub.2015.05.047
  • Saguez, J., Lemoyne, P., Giordanengo, P., Olivier, C., Lasnier, J., Mauffette, Y., and Vincent, C. (2015). Characterization of the feeding behavior of three Erythroneura species on grapevine by histological and DC-electrical penetration graph techniques. Entomol Exp Appl 157, 227–240. DOI:10.1111/eea.12353

Chapitres d'ouvrages et autres publications


  • Beaulieu R., Attoumbré J., Gobert-Deveaux V., Grand E., Stasik I., Kovensky J., Giordanengo P. Novel solanidine derived compounds. WO2015/008007 (A1); 2015 January 22 (brevet)

Danila Cabral, Mohamed Youssef Banora, José Dijair Antonino, Natalia Rodiuc, Paulo Vieira, Roberta Ramos Coelho, Christian Chevalier, Thomas Eekhout, Gilbert Engler, de Lieven De Veylder, Maria Fatima Grossi‐de‐Sa and Janice de Almeida Engler. (2020). The plant WEE1 kinase is involved in checkpoint control activation in nematode‐induced galls. New Phytologist, 225(1), 430-447. Doi:10.1111/nph.16185.

Archive 2014-2006

2014-2006 publication list
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