BES | Bioinsecticides, Environnement et Santé head: Armel GALLET |

| The team is interested in the mechanisms of defense of an organism against environmental aggressors and the pathophysiological consequences when those mechanisms failed. Focusing on host-pathogen interactions, we are studying gut physiology, intestinal stem cell functions in the maintenance of cellular homeostasis and innate immunity in Drosophila melanogaster. | |
| Pierre BARBERO Alexandra BRUN-BARALE Marie-Paule ESPOSITO Arnaud FICHANT | Armel GALLET Salma HACHFI Aurélia JOLY | Nathalie PASCAL-ZUCCHINI Raphaël ROUSSET Fatima TLEISS |
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BPI | Biology of Introduced Populations head: Elodie VERCKEN |

| The lab studies the conditions for the installation and the evolution of introduced populations of insects. Our biological models are invasive pests and species used in biological control. Our research on introductions, subsequent demographic and geographic expansions, and the associated evolutive phenomena, is based on ecology and evolutionary biology. We combine behavioural ecology, population genetics and population dynamics. | |
| Alexandra AUGUSTE Aurélie BLIN Didier CROCHARD Emeline DELEURY | Géraldine GROUSSIER Chloé GUICHARNAUD Thomas GUILLEMAUD Laurent LAMY | Eric LOMBAERT Thibaut MALAUSA Barbara PORRO Elodie VERCKEN |
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CEA | Community Ecology in Agrosystems head: Nicolas DESNEUX |

| The CEA team is questioning the Community Ecology in Agrosystems for fundamental research interests but also in order to improve IPM (Integrated Pest Management) and particularly biocontrol strategies. | |
| Marcel AMICHOT Philippe BEAREZ Roger BOLL Nicolas DESNEUX | Kouassi Arthur Jocelin KONAN Anne-Violette LAVOIR Ruo-han MA | Lucie MONTICELLI Cliven NJEKETE Antoine PASQUIER |
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DEB | Developmental timing, Environment, and Behaviors head: Nuria ROMERO |

| Our interest focuses on understanding how does the environment interact with the genes to times the Juvenile-to-adult DevelopmentalTransition (JDT) and its associated behaviors. The JDT (Metamorphosis/ puberty) determines the reproductive ability for a given species. Therefore, uncovering the mechanism timing this developmental transition is essential to improve pest management efficiency but also, in the case of human, to battle against adverse health consequences caused by earlier puberty. | |
| Raphaël BONCHE | Nuria ROMERO | Eleanor SIMON |
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EQA | Support team head: Catherine AUGUET-CHADAJ |

| The support team provides outreach service to the research teams and technical units of the ISA unit. Made up of 14 people and placed under the responsibility of the administrator. | |
| Stephen AMBROGIO Catherine AUGUET-CHADAJ Séverine BEURTEY Pascale BOISSELIER Nathalie BOSSELUT-BENOIT Yasmine CARRASSET | Christelle DELALLEAU Sylvie FILIPLICH Paulette FLACCHI Pascal GORY Nathalie MARTEU | Emmanuelle MURCIANO GERMAIN Sylvain NUEE Frédéric POTIER Christian REBUF Elodie WESPIESER |
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ESIM | Evolution and Specificity of Multitrophic Interactions head: Marylène POIRIE |

| The team aims at deciphering the physiological and molecular bases of the specificity of multitrophic interactions involving insect hosts, associated bacterial symbionts, and parasitoid wasps. Our research projects focus for instance on: the insect immune response and how it is possibly modulated by bacterial symbionts, the evolution of virulence factors from venom of Hymenopteran parasitoids, or the role played by extra-cellular vesicles in the transfer of information between host and parasitoid species. | |
| Laury ARTHAUD HUGONIN Goodluck BENJAMIN Dominique CAZES | Isabelle DEYDIER Jean-Luc GATTI Séverine LEMAUF | Marylène POIRIE Sophie TARES-AMICHOT |
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FIORIMED | Multi-performance des cultures horticoles protégées head: Christine PONCET |

| Non renseigne | |
| Séverine DOISE Jean-Marie DRAPIER | Valérie FRANDON Christine PONCET | Sophie VOISIN |
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GAME | Genomics & Adaptive Molecular Evolution head: Etienne DANCHIN |

| The GAME team studies mechanisms of genomic plasticity related to: 1 - species evolution towards a parasitic or pathogenic life style and 2 - adaptation of these same species to current environmental changes, including to methods deployed to manage them.Scientists in GAME use bioinformatics, biostatistics and artificial intelligence for their research. | |
| Marc BAILLY-BECHET Carole BELLIARDO Dominique COLINET | Etienne DANCHIN Djampa KOZLOWSKI Marine POULLET | Karine ROBBE-SERMESANT Ana Paula ZOTTA MOTA |
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GEP | Project team "Genetics, Environment and Plasticity" head: Alain ROBICHON |

| One objective of the team is to use the aphid model to determine the components of epigenetic regulation leading to adaptation to the environment. Our aim is to determine whether epigenetic marks, in particular genome methylation, induced by an extreme climate phase might be heritable across clonality (spring and summer) and also whether this heritability might pass the sexual barrier (fall and winter) to be transmitted in the newly emerged clonal generations the next spring, in order to achieve adaptation. | |
| Jean-Jacques REMY | Alain ROBICHON | |
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ID | Insect Defence head: Christine COUSTAU |

| The management of insect pests, from phytophagous and parasites to disease vectors requires a thorough knowledge of the mechanisms by which insects deal with chemical and biological challenges. These challenges to insect fitness can be viewed as a seamless range of aggressions, rather than categories of "pathogens" or "xenobiotics". The overall goal of our team is to exploit genomic resources to study the functional basis of insect defense mechanisms and their evolution. | |
| Christine COUSTAU Janice DE ALMEIDA-ENGLER Ariane FAZARI Thierry FRICAUX | Philippe GIORDANENGO Frédérique HILLIOU Gaëlle LE GOFF Killian MENUET | Olivier MIGLIORE Tae Sun MIN Bernard MOUSSIAN Roxanne PICHOT |
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IPN | Plant-Nematode Interaction head: Bruno FAVERY and Stéphanie JAUBERT-POSSAMAI |
| The overall objective of the team, through various levels of study ranging from the gene to the field, is to acquire the scientific basis for a better understanding of the interaction between the plant and the nematode in order to envisage new specific, sustainable and environmentally friendly control methods. The research developed concerns the two partners in the interaction, i.e. the plant, with the study of the development of the disease (susceptibility) or the establishment of resistance, and the parasite, with the analysis of the pathogenicity and its capacity to evolve. | |
| Pierre ABAD Claire CARAVEL Philippe CASTAGNONE Caroline DJIAN-CAPORALINO Bruno FAVERY Pauline FOUBERT | Rahim HASSANALY GOULAMHOUSSEN Stéphanie JAUBERT-POSSAMAI Ulysse JULIEN-PORTIER Sophie MANTELIN Karine MULET Cliven NJEKETE | MICHAEL QUENTIN Sarah RANTY-ROBY Salomé SOULE Cyril VAN GHELDER Laetitia ZURLETTO |
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IPO | Plant-Oomycete Interactions head: Eric GALIANA |

| The team is currently studying mechanisms underlying interactions between plants and microbes in order to contribute to alternative pest control strategies. Our research programs, mainly conducted on plante-oomycete* interactions, aim at identifying molecular processes that orchestrate, on the pathogen side, the onset and the development of infection and the associated evolutive processes. We also aim at deciphering plant responses, leading to the success (sensitivity) or the failure (resistance) of the infection. We combine plant pathology, cell biology, evolutionary and functional genomics, biochemistry and molecular biology. | |
| Valerie ALLASIA Agnès ATTARD Aurélien BOISSON DERNIER Alexandre BRUNET Catherine ETIENNE Eric GALIANA | Celso GASPAR LITHOLDO JUNIOR Laïla GIORDANO Benoit INDUSTRI Harald KELLER Marie-Line KUHN | Jo-Yanne LE BERRE Carlotta Aurora LUPATELLI Naïma MINET Franck PANABIERES Enora PANEK |
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M2P2 | Models and Methods for Plant Protection head: Ludovic MAILLERET |

| The team aims at making plant protection more respectful of the environment through the development of innovative ecological pest management strategies. For that purpose, the team develops an interdisciplinary research program based on the concerted use of theoretical models and experiments to address specific issues from the individual to populations and agroecosystems. | |
| Valentina BALDAZZI Cécile BRESCH-BARRAYA Vincent CALCAGNO Mélina COINTE | Marine COURTOIS Laurent KREMMER Ludovic MAILLERET Lydia OTTENWAELDER | Guy PEREZ Suzanne TOUZEAU Louise VAN OUDENHOVE |
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RDLB | Research and Development in biological control head: Xavier FAUVERGUE |

| The main objective of the team "Research and Development in Biological Control" is the field implementation of biological control strategies against noxious phytophagous insects using entomophagous insects (parasitoids or predators). | |
| Nicolas BOROWIEC Alexandre BOUT Lucas BROWET Xavier FAUVERGUE | Michela ION SCOTTA Philippe KREITER Karolina PECHAROVA Nicolas RIS | Cassandre VIDAL Sylvie WAROT Gabriel ZIZZO |
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SYMBIOSE | Legume-Rhizobium Symbiosis: cellular redox status head: Pierre FRENDO |

| The team focuses on improving our knowledge of plant/nitrogen-fixing bacteria (Rhizobium) by studying the role of the cellular redox state during the symbiotic interaction. | |
| Geneviève ALLOING Goodluck BENJAMIN Eric BONCOMPAGNI Alexandre BOSCARI Marc BOSSENO Renaud BROUQUISSE | Chaïma CHAMMAKHI Alexandre DEMBA Laurence DUPONT Pierre FRENDO Isabelle GARCIA Didier HEROUART | Marc LEPETIT Karine MANDON-ANTIER Fanny NAZARET Marie PACOUD Nicolas PAULY |
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