Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free: https://www.ghostery.com/fr/products/

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site: http://www.youronlinechoices.com/fr/controler-ses-cookies/, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Realytics
Google Analytics
Spoteffects
Optimizely

Targeted advertising cookies

DoubleClick
Mediarithmics

The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at cil-dpo@inra.fr or by post at:

INRA
24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Institut Sophia Agrobiotech Logo Marque Etat - République Française Logo_INRAE_noir Logo Université Côte d'Azur CNRS

Home page

Institut Sophia Agrobiotech

UMR INRA - Univ. Nice Sophia Antipolis - Cnrs

http://www.paca.inra.fr/institut-sophia-agrobiotech_eng/

RNAs involved in the establishment of giant cells

Friday, 5 February - 11:00 - Sophia Antipolis - Inra PACA - Room A010

Séminaire scientifique
As part of the scientific activities of the Institut Sophia Agrobiotech, Clémence Medina (PhD in IPN team), will present her work : "Characterization of small regulatory RNAs involved in the establishment of giant cells induced by parasitic nematodes of genus Meloidogyne"

Abstract

Plant response to bioagressors involves modifications of gene expression. Recently, microRNAs have been evidenced as crucial regulators of host gene expression during plants-pathogen interactions. Root-knot nematodes (RKN) are biotrophic plant parasitic worms that transform plant cells from root vascular cylinder into hypertrophied, multinucleate and highly metabolically active giant feeding cells. Since RKN are able to induce the formation of feeding cells in roots of almost all cultivated plants, they are thought to manipulate essential and conserved plant molecular pathways. Previous transcriptomic analyses evidenced that redifferentiation of root cells into giant feeding cells implies transcriptional reprogramming with a large repression of gene expression. Our study aims to investigate the role of microRNAs in the regulation of transcriptional repression observed during the redifferentiation into feeding cells. Small RNAs from Arabidopsis thaliana roots infected with the RKN model species Meloidogyne incognita were sequenced by SOLID technology. As a control, small RNAs from non infected roots were also sequenced. First, a catalog of microRNA expressed in healthy and infected roots was established. Then, microRNAs that are differentially expressed between healthy and infected roots were then identified by EdgeR statistical analyses. Preliminary results identified 24 microRNAs that are differentially expressed in infected roots and statistically relevant. Some of these microRNAs are known to be involved in plant responses to biotic and abiotic stress or in hormone-dependent process. Our results suggest that microRNAs are involved in the regulation of gene expression that results in redifferentiation of root cells into giant feeding cells.