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INRA
24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

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ZAFIROV Delyan

Student - PHD

Zafirov
Equipe ReDD

Research focus

I am a PhD student working for the French National Institute for Agricultural Research in the laboratory of Genetics and Breeding of Fruit and Vegetables (GAFL).

My research focuses on the development of loss of susceptibility resistance to potyviruses based on eIF4E translation initiation factors, important host components required for the virus infection. By using the Arabidopsis/potyvirus pathosystem, I am studying how potyviruses interact with these factors on the biochemical level. Understanding these mechanisms could help the generation of a more efficient resistance to be deployed in crops.

Field of expertise: Plant pathology, virology, molecular biology, genetics

Education

Since October 2018: PhD student under the doctoral supervision of Jean-Luc Gallois at INRA - GAFL

2016 - 2018: Master’s degree in Plant Biology and Biotechnology at Aix Marseille University

2013 - 2016: Bachelor’s degree in Life Sciences at François Rabelais University

Professional experience

January - July 2018: Internship at INRA - GAFL, Avignon, France

 

Research topic: Characterization of novel virus resistances in Arabidopsis by development of synthetic alleles

 

Internship supervisor: Jean-Luc Gallois

May - July 2017: Internship at INRA - Fungal Biodiversity and Biotechnology, Marseille, France

 

Research topic: Adaptative response of xylophagous fungi to wood degradation and transcriptional regulation of defense genes

 

Internship supervisor: Marie-Noëlle Rosso

 

July 2015: Internship at AgroBioInstitute, Sofia, Bulgaria

 

Research topic: Identification of phytopathogenic organisms by molecular techniques

 

Internship supervisor: Slavtcho Slavov

 

June 2015: Internship at BAS - Stephan Angeloff Institute of Microbiology, Sofia, Bulgaria

 

Internship supervisor: Penka Petrova

 

Publications

Bastet, A., Zafirov, D., Giovinazzo, N., Guyon-Debast, A., Nogué, F., Robaglia, C., Gallois, J.-L. (2019). Mimicking natural polymorphism in eIF4E by CRISPR-Cas9 base editing is associated with resistance to potyviruses. Plant Biotechnology Journal. , DOI: 10.1111/pbi.13096

https://prodinra.inra.fr/record/465122

Scientific workshops

17th EUCARPIA Meeting Genetics and Breeding of Capsicum and Eggplant, 11-13th September 2019 - Avignon, France

Journées Jeunes Chercheurs (BAP), 13-14th June 2019 - Avignon, France (Oral presentation)

17emes Rencontres de Virologie Végétale, 27-31st January 2019 - Aussois, France (Oral presentation)